The Enbrel SureClick autoinjector (50 mg/mL etanercept) is intended for self-administration of Enbrel in the treatment of autoimmune conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, and plaque psoriasis

Key Features:

1. Prefilled & Ready-to-use: No manual loading; comes preloaded with a 50 mg dose of etanercept.

2. Visual Feedback: A viewing window allows you to monitor injection progress — fully yellow when done

3. One-button activation: Press the device against the skin, push the purple start button, hold until the window turns yellow — the injection is complete

4. Safety features: The green safety guard protects the needle, locking automatically after injection. The white cap should only be removed just before use and never recapped

5. Storage & Handling:

   • Keep refrigerated at 2 °C to 8 °C (36 °F to 46 °F) until use.

   • After removal, allow autoinjector to reach room temperature (approx. 30 minutes); do not heat or freeze.

   • Once at room temperature, use within 30 to 14 days depending on guidance; do not return to fridge

Step-by-Step Injection Overview:

1. Preparation: Ensure you've been trained. Check expiry date, carton integrity, and clarity of the solution Gather supplies: alcohol wipe, cotton/gauze, bandage, sharps container

2. Injection Sites: Thigh, abdomen (avoiding a 2-inch area around the navel), or upper arm (if administered by another person)

3. Injection Process:

   • Remove white cap, place against skin at 90° angle.

   • Press down firmly: safety guard will release the purple button.

   • Press the purple button—hold until window turns fully yellow (~15 seconds). Click sounds may signal start and end

   • After the window turns yellow, withdraw device, check site (do not rub), apply bandage if needed 

   • Dispose in sharps container

Safety Precautions:

• Do not shake, freeze, or drop the device.

• Discard if expired, damaged, or solution appears discolored or cloudy 

• Not for use in children under 138 lb (63 kg) for certain conditions

• May suppress the immune system, increasing risk for serious infections — your healthcare provider will monitor accordingly